If you are a beginner it is always better to start play on any number of pay lines and reels. If you play many paylines increase your risk, which can be dangerous to your finances. It is always tempting to bet big in hopes of winning the jackpot, but this also means that the losses will be much greater. Winning at slots is not easy, and the random number generator will not help you.
Remember that you play to have fun because if you play for the jackpot you will be disappointed. And if by chance you pick up the prize you will certainly feel better if you do not think about all the losses to get there.